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[textualdeviance]

Testosterone is converted to estrogen in fat cells, therefore burning a fat cell will release estrogen, which will cause an excess of free-floating estrogen, which in turn causes endometrial hyperplasia/hypermenorrhea. Untreated, endometrial hyperplasia can lead to endometrial cancer.

Estrogen dominance syndrome

Failure to eliminate estrogen: Liver's ability to neutralize estrogen to eliminate it from the body can be impaired by various causes.

Excessive conversion of progesterone to other hormones: Stress coping hormones such as cortisone are produced from progesterone. Thus, high stress can reduce the effects of progesterone and shift the hormone production in favor of other hormones. Large doses of progesterone have anti-stress effects and protect adrenal gland.

Problems converting fat cells to glucose? Leptin? Or enzyme?

Comments

[cherryheavy.livejournal.com]

So then, when losing weight, or more specifically, burning fat cells that release excess estrogen, one should be taking progesterone suppliments? They've wanted to put me on progesterone, but I refused- adding chemicals to my body turns me into a suicidal maniac.

Re:

[textualdeviance.livejournal.com]

Birth-control pills did that to me-- but it was because of the excess estrogen. I've been avoiding the doctor lately because of a bad experience a couple of years ago, but they used to have me on a progesterone supplement that I took when I started bleeding too much, and it did make a difference, at least for that aspect of things, and it didn't make me crazy. Basically, if you're not ovulating, you're not producing progesterone, and your body needs that to counteract the effects of the estrogen. Plus with PCOS, you have excess estrogen floating around anyway because your body thinks your ovaries aren't producing enough, so it starts secreting estrogen from the adrenal glands, plus making you store abdominal fat, which has a higher concentration of estrogen than other fat stores.

Theoretically, at least, from everything I've read, and heard from my docs so far.

Most of the time they put PCOS patients on birth-control pills because they don't bleed, and that makes them bleed regularly, but when you have the opposite problem, throwing more estrogen at it just makes things worse. I was really surprised once, when my doc told me that PCOS patients have not only excess androgens (testosterone, etc.) but excess estrogen, too. I'd always been under the impression that the excess androgens meant a correspondingly lower amount of estrogen, but that's not the case. It's not a balance or anything, where a high amount of one means a low amount of the other. If anything, progesterone is the one female hormone that tends to be deficient.

Re:

[cherryheavy.livejournal.com]

Dig. I've seen some teas that the hippies make that has a natural progesterone suppliment. I was bleeding regularly for quite a few months in a row, and then back in August is just stopped, and I haven't blead since.

It's frustrating. Just as my DR dropped me, we were starting to get to the bottom of my female problems and taking steps to make things work. Stupid insurance. I'd really like to be healthy.

How do you handle the constant bleeding? It would drive me batshit insane.